Garcinia Cambogia for Weight Loss: Effectiveness & Safety

There is an ample number of research studies dedicated to the weight loss benefits of Garcinia cambogia, but there have been varied results. Most studies show either a limited number of participants or a very specific overweight or obese participant sample.

A 3-month study administered Garcinia cambogia to 99 obese men, along with a proven drug for weight loss called orlistat. It was found to reduce BMI, visceral or belly fat, subcutaneous fat, and waist circumference [R].

Two 12-week research studies showed that in 89 mildly overweight adult participants, Garcinia cambogia resulted in a 3.7-kilogram weight loss, 1.3 kilograms more compared to the placebo. In 20 obese adult participants, it reduced weight by 3.5 kilograms, which was 85% fat [R] [R].

In a 16-week placebo-controlled study, Garcinia cambogia extract lowered total body fat, belly fat, and subcutaneous fat in 18 adults. The same cannot be said of the placebo group consisting of 21 adults [R].

Two 8-week studies show that hydroxycitric acid found in Garcinia cambogia resulted in a 5%-6% reduction in weight and BMI in 60 moderately obese adults and 5.4% in 82 significantly obese adults [R] [R].

Another study that ran for 8 weeks found that Garcinia cambogia resulted to more fat reduction (belly and subcutaneous) than the placebo in 40 obese adults [R].

In a 2-month study, Garcinia cambogia extract supplementation resulted in a 4.67% decrease in body weight in 30 overweight and obese adults, where the 28 adults taking placebo only had a 0.63% decrease on average [R].

In a 2-week study, hydroxycitric acid reduced the body weight of 21 obese adults [R].

However, in the following cases, there was no significant weight loss noted:

A 12-week trial study involving 135 overweight adults showed that the hydroxycitric acid in Garcinia cambogia failed to result in more fat or weight decrease compared to the placebo [R].

A 10-week study involving 86 overweight adults also yielded the same results [R].

Hydroxycitric acid did not have any relevant results on the carbohydrate and fat breakdown of 10 cyclists [R].

Dangers of Garcinia Cambogia

Case reports have shown that a daily dosage of 240 to 500 mg hydroxycitric acid resulted in acute liver disease or irreversible liver damage [R] [R] [R] [R] [R].

Garcinia cambogia caused symptoms of psychosis and mania, such as delusions, lack of self-awareness, hyperactivity, and rapid speech, in individuals with or without a history of psychiatric illnesses [R] [R] [R] [R].

Garcinia cambogia caused a 48-year-old woman to have an arrhythmia or irregular heart rate, myocarditis or heart muscle inflammation, and heart failure [R].

A 51-year-old woman was admitted at a hospital due to hypertension and cardiomyopathy after oneweek supplementation of Garcinia cambogia [R].

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